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Neurotrophic factors hold promise for the future of Parkinsons disease treatment: Is there a light at the end of the tunnel

10 Mitochondrial Function NAD+ metabolism is intricately linked to mitochondrial function

In the context of peripheral nerves, thiamine deficiency impairs axonal conduction and myelin maintenance, leading to neuropathic symptoms [10,12]

We found no difference in the expression of MBP or MOG with treatment of slices with CPZ alone or CPZ + rapamycin, suggesting rapamycin had no further effect on the demyelination produced with CPZ treatment alone