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PET and MR imaging of neuroinflammation in hepatic encephalopathy

The plasma exosomes from patients with primary Sjgrens syndrome contain epithelial cell-derived proteins involved in ferroptosis

Interestingly, interventions that boost NAD + levels resulted in extended lifespan in worms and mice 108,109,111,247 , suggesting a therapeutic potential for raising NAD + in various pathological conditions or age-associated diseases

By clearing FAP+ CAFs, eNV-FAP significantly reduces the number of immunosuppressive cells (such as M2-type TAMs, MDSCs, and Tregs) in the TME, thereby reversing the immunosuppressive state and enhancing antitumor immune responses ( + T-cell activity, inhibit tumor growth, and prolong animal survival ( in vitro -derived TAMs by decreasing CD163 expression ( in vivo ( In addition to the construction of nanomaterials, a significant amount of research has focused on the development of nanoplatforms to target GBM and enhance immune responses for therapeutic effects, as shown in Table 1