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As well, KYNA-induced inhibition of 7nAChRs reduces presynaptic glutamate release, thereby indirectly dampening AMPAR activation, a mechanism that may protect neurons from glutamate-driven excitotoxicity under pathological conditions [82]

However, this correlation might not extend to Western cultures where the predominant consumption of the common button mushroom ( Agaricus bisporus ) is lower in ergothioneine

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

Hydrogels are three-dimensional (3D) cross-linked networks formed by physical or chemical cross-linking of hydrophilic polymers (e.g., polysaccharide-based matrices such as chitosan, sodium alginate and cellulose derivatives), featuring high water content, good biocompatibility, and tissue-like physicochemical properties reminiscent of the natural extracellular matrix (ECM) [20,21]