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Description

Genetic engineering for introducing glutathione synthesis ability in Lc

Under hypoxic conditions, the inactivation of PHD2 in human PAECs increases HIF-2, thereby enhancing NAMPT promoter activity to raise the expression of Snail1 and decrease the expression of PECAM1, ultimately inducing EndMT

Additionally, synthetic agents targeting Janus-activated kinase (JAK) inhibitors and cell therapies utilizing mesenchymal stem cells (MSCs) have been incorporated into RA treatment protocols (2931)