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doi: 10.3389/fphys.2018.00835

The study was based only on data from the published literature, did not allow for prospective or randomized controlled trials, and did not explore the direct associations between drug penetration ratios and adverse fetal or neonatal outcomes

Preclinical research has demonstrated the anti-inflammatory and anti-neuroinflammatory properties of various phytocannabinoids, and in addition, has identified a plethora of mechanisms that could mediate the actions of these compounds

Moreover, some ATF members can directly or indirectly recruit ATP-dependent chromatin-remodeling complexes, altering nucleosome positioning and conformation to reorganize the chromatin landscape (112)