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Description

Manufactured with batch-level controls and laboratory packaging so scientists can rely on purity, accuracy, and consistency

this system can be manual or fully automated

Once-weekly subcutaneous injection, escalated in phases from 0.25 mg up to ~4.5 mg

In the basal state PNPLA2 has weak hydrolytic activity which is greatly increased by the co-lipase alpha/beta hydrolase domain-containing protein 5 (ABHD5, also known as CGI-58) by greater than 20-fold (30)