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As a result, underlying mechanisms of them are sequentially connected, even though their primary goal is different respectively

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The phosphorylation of GluN2B at Tyr1472 by Cdk5 promoted receptor internalization (Zhang et al., 2008), similarly phosphorylation of regulatory site Ser1116 also inhibited the membrane trafficking of GluN2B-containing NMDARs (Plattner et al., 2014)

A minimum of 100 worms were picked for each condition for every repetition to ensure sufficient number after censoring stragglers, bagged worms, and worms killed during transfer