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2016 Oct 25 [cited

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166,167 The pathophysiology of diabetic mononeuropathy includes ischemic mechanisms, such as the occlusion of the vasa nervorum leading to nerve infarction, metabolic factors, including hyperglycemia-induced oxidative stress, and the formation of advanced glycation end products, contributing to nerve damage

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The main sources of ROS are mitochondrial respiratory chain and NADPH oxidase [48]

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