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Oracea is a prescription medication commonly used to treat the inflammatory lesions of rosacea, a chronic skin condition that causes facial redness, inflammation, and visible blood vessels

Data availability No datasets were generated or analyzed during the current study

Yesits described as allnatural, safe for humans, fish, wildlife and plants

25-OHC treatment significantly inhibited sterol regulatory element-binding protein (SREBP) expression in IMS32 Xuewang cells, downregulated GXP4 and stearoyl-CoA desaturase 1 (SCD1), and upregulated PTGS2, thereby increasing intracellular ROS levels and promoting ferroptosis