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Collectively, the composition, metabolic activity, and functionality of the gut microbiota significantly affect the metabolism of GLs

Jiao X et al (2021) Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

A recent study on mouse skeletal muscle aging based on mass cytometry observed that CD47 hi MuSCs occur with a higher frequency in aged mice and exhibit poor regenerative capacity 24

The downstream consequences include enhanced glucose uptake into skeletal muscle independent of insulin, increased fatty acid oxidation, and suppression of inflammatory signaling