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There is a possible link between potential oxidant effects of nicotine demonstrated in this study and its modulation of ALP mediated actions 47 , collagen and ECM formation in fibroblasts 50 , which could contribute to the effects of nicotine on wound healing, applicable to the cells used in our investigation

Since iron is important to ferroptosis, the specific iron mechanism has attracted a new wave of attention

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Intravenous use of glutathione has also been tremendously helpful, especially in the onset of treatment of toxicity