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Methods Patients and tumor samples After obtaining written informed consent, surgical specimens and clinical records were obtained from 16 patients with gliomas who had surgery to remove brain tumors at the First Affiliated Hospital of Chongqing Medical University (Chongqing, China), in accordance with the appropriate Institutional Review Boards (Table 1)

10.1038/cddis.2016.208 153 MaiorinoM.ConradM.UrsiniF

Composition of Bio Rae Complexion 12: Glutathione (5000mg) 10ml vials

Mutational analysis 5 M of TERRA23 rG4s, dissolved in NaPi buffer, were mixed with equimolar concentrations of wild-type and different lysine-alanine mutant SERF2 and incubated for 30 min at room temperature