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Searches of PubMed and ClinicalTrials.gov did not identify a peer-reviewed study or registered clinical trial of the exact four-component KLOW formulation reviewed for this article

For the B 12 bolus experiment, mice were administered 5 g vitamin B 12 (Sigma, V2876) dissolved in water by oral gavage on day 6 after the start of doxycycline treatment, and blood samples were taken by submandibular collection just before and 24 h after the bolus

Human Correlation: Findings from a 2023 human study found that a higher serum MOTS-c concentration correlated with "greater muscle mass, force, and power generated during jumping" in healthy subjects

Used during peak bodybuilding years : While its not as hyped today, glutamine was a staple in early 2000s bodybuilding, and Cutler credited it as one of his most-used recovery aids