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AOD-9604 received "Generally Recognized As Safe" (GRAS) status from the US FDA for use as a food ingredient, which is a limited regulatory recognition but is notable it means the FDA has reviewed some safety data for this compound

Adebayo EA, Azeez MA, Alao MB et al (2021) Fungi as veritable tool in current advances in nanobiotechnology

For example, a reduced DNA damage response capacity was observed in lymphomas of Golden retriever dogs (Thamm et al., 2013), and a lower expression of the ATM serine/threonine kinase ( ATM ) gene was found in canine mammary tumors (Raposo-Ferreira et al., 2016)

(Cochrane Drugs and Alcohol Group) (February 2010)