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However, G6PD reportedly undergoes modifications such as phosphorylation at Y112 and Y428 [69, 70] in HCT116 cells, acetylation at K403 [71] in leukaemia cells and glycosylation at S84 in lung cancer cells [72]

Such GPX4-independent surveillance pathways are often mediated by enzymes that generate metabolites with radical-trapping antioxidant (RTA) activity, including ferroptosis suppressor protein 1 (FSP1), dihydroorotate dehydrogenase (DHODH), and GTP cyclohydrolase-1 (GCH1), etc 10,14,15,16

Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension

Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions