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Changes apply prospectively unless law permits otherwise

Much of it comes from the same investigators or research networks

*Correspondence: Agata Blazewicz, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Both selective AMYR agonists, and dual CTR and AMYR agonists such as sCT 5,6,7 , have demonstrated efficacy in controlling appetite and body weight, however this is not seen with a CTR-selective agonist 9