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Metformin use is associated with a reduced risk of mortality in patients with diabetes hospitalised for COVID-19

In the liver, feeding-induced FXR activation elevates SHP expression, which forms a complex with CREB to recruit lysine-specific demethylase 1 (LSD1) to the promoters of ATGs such as Tfeb, Ulk1 , and Atg7

As a result, eating mushrooms regularly is associated with a reduced risk of cancer

We reduced the dimensionality of the chromatin accessibility data by latent semantic indexing, by first normalizing using the term frequency-inverse document frequency (TF-IDF) normalization method, followed by a singular value decomposition using all peak features implemented in Signac