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Description

Replacement of the conserved asparagine by alanine resulted in constitutive p300 interaction and strong transcriptional activity

Vegetarians and individuals over 50 face particularly elevated risk, as do people with digestive conditions affecting nutrient absorption

Western blot analysis Samples were resuspended in 6x Laemmli buffer and loaded onto an SDS-PAGE for protein separation, followed by transfer to a nitrocellulose membrane with the wet blot method