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Dysesthesia occurred in 22.9% of participants at the 7.2mg dose versus only 6% at the 2.4mg dose and 0.5% with placebo

In addition, within cells, a series of regulatory mechanisms are involved in redox processes, such as the Keap1/Nrf2 transcription factor, NF-B signalling, the MAPK pathway, PI3K-Akt cascades, and the AMPK-mTOR axis [6, 7]