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Reaction of the imidazole ring of histidine with HOCl (with a second-order rate constant k = 8.0 10 4 M 1 s 1 [228]) leads to the formation of a short-lived chloramine

It may take 20 or more weeks to reach the maximum dosage (15 mg once weekly), depending on your bodys tolerance

We believe that this is the best available data for use in calculating the proposed median number of discharges by region and is consistent with our data proposal to use cost report data from cost reporting periods beginning during FY 2021 for FY 2024 ratesetting