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Excessive generation of reactive oxygen species (ROS) has been identified as a major pathological driver, sustaining pro-inflammatory cascades and compromising fibroblast functionality, thereby underscoring the critical role of redox balance and antioxidant-based interventions in promoting regenerative healing

Int J Cancer 127:18131822 Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH et al (2013) ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Elastin cross-linking with other ECM components and the enzymes governing this process all have effects on tumorigenesis

The study looked at taurine levels in mice, monkeys, and humans and found that levels decline with age