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Estrogen enhances female small intestine epithelial organoid regeneration

The mean and median durations of partial response were 810 and 430 days, respectively

doi: 10.1155/2019/9613090 29 PisoschiAMPopA

This observation is not surprising as the cereblon ligands are very similar to thalidomide, both containing multiple lactam moieties, and the non-enzymatic hydrolysis of thalidomide has been long understood (Schumacher et al