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Avoid strenuous activities, especially ones that may cause pain or stress the muscles too much

This mechanism represents a fundamentally different approach to fat metabolism compared to appetite suppression (GLP-1 agonists) or direct lipolysis stimulation (growth hormone peptides)

Previous FDA panels on the topic have been composed of academics and researchers

If the GLP-1/GIP/glucagon receptor class shows disease-modifying behaviour in OA rather than just mechanical pain relief from weight loss, it expands the scientific rationale for the compound and reinforces the argument that the triple-agonist mechanism is doing more than suppressing appetite