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However, existing PTT monotherapies are not effective (Wang L

The term "effective" amount or a "therapeutically effective amount" of a drug or pharmacologically active agent is meant a nontoxic but sufficient amount of the drug or agent to provide the desired effect

10.1016/j.bbrc.2011.08.007 Biochem

The GHK sequence also appears within the alpha-2(I) chain of type I collagen, leading to the hypothesis that collagen degradation at wound sites releases GHK fragments that then bind copper and signal for new collagen production, creating a self-repair feedback loop