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Images corresponding to each sample were averaged to obtain the mean adipocyte area (m 2 ) per sample and combined to calculate group mean values for control (vehicle-treated EWAT samples) and treatment (NNMT inhibitor-treated EWAT samples) cohorts

Preclinical studies in diet-induced obesity models demonstrated 5-Amino-1MQ reduced body weight by 7% and increased energy expenditure by 9% over 11 days without dietary changes

Because high-quality safety data for subcutaneous lipotropic therapy is still limited, its especially important to report any unusual or persistent symptoms to your care team and to seek prompt medical attention for severe reactions such as difficulty breathing, chest pain, or signs of an allergic reaction

MEASUREMENTS AND MAIN RESULTS: Statistically significant alterations in serum values for aspartate aminotransferase, total bilirubin, creatinine, magnesium, and iron were seen in the presence of OHCob