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In a sciatic nerve IRI model, oral administration of lutein before ischemia and after reperfusion reduced neuropathic pain and nerve injury by decreasing oxidative stress and suppressing inflammatory mediators, such as NF- B and TNF- , while preserving endogenous antioxidant defenses [56]

Similarly, a pilot study in 2015, a clinical trial (randomised) on 42 healthy human participants, receiving oral (tablet form) dosages of BPC 157 was carried out (Clinicaltrials.gov 2018): 0.25, 0.5, 1 and 2 g/kg

PMID: 32019204

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