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When combining the two, their benefits can complement each other

Vitamin B12 deficiency is a recognised nutritional complication following bariatric surgery, including gastric banding (laparoscopic adjustable gastric banding, LAGB)

This allows distal signals (from axon health and target connections) reaching nucleus influencing gene expression

The term NNMT inhibitors as used herein refers small molecule chemical entities that inhibit the enzymatic activity of NNMT, and includes the compounds of Formula I and Formula IA as well as compounds in Tables 1-3