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doi: 10.1038/ng.2982 33 ChmurzynskaASeremak-MrozikiewiczAMalinowskaAMRozyckaARadziejewskaASzwengielAet al

To identify glutathione-overproducing mutants, acrolein was used as a selective agent, given glutathiones key role in protecting cells from acrolein-induced toxicity (Mano et al., 2009

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18 Continued efficacy was confirmed in a similar study in which Psoriasis Area and Severity Index (PASI) score improvements of at least 50%, 75%, and 90% was shown to be achieved by increasing percentages of participants over a period of years