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Neonatal opioid withdrawal syndrome presents as irritability, hyperactivity, abnormal sleep pattern, high-pitched cry, tremor, vomiting, diarrhea and failure to gain weight

A vial that was sterile when compounded may harbor bacteria, fungi, or other microorganisms weeks or months after the BUD, especially if it has been punctured multiple times

Publication and enthusiasm bias Finally, much of the accessible GHK-Cu literature is authored by a small number of closely associated researchers and enthusiasts, and negative or null results are less likely to be published or promoted

However, an underlying problem of this model is that results identified in rodents may not parallel what is seen in humans