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Additionally, the rapid therapeutic effect of BPC 157 is evidenced by rapid reversal of the negative chain of events (Vukojevic et al., 2018)

This mechanism raises the critical discontinuation question - does stopping GHK-Cu immediately halt enhanced collagen production returning synthesis rates to pre-treatment baseline, or does the improved dermal environment created during treatment continue supporting elevated collagen production through positive feedback mechanisms where better matrix structure itself promotes ongoing synthesis even without continuous peptide stimulation

After completing the 20-day cycle, researchers observe a washout period of 4 to 6 months before the next cycle

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