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424 In AD, GLP-1(7-36) amide inhibits IL-1 transcription and prevents cognitive dysfunction, amyloid precursor protein synthesis, and cell death

LDN refers to naltrexone taken at roughly 1.5 to 4.5 mg daily, about one-tenth the standard 50 mg dose

These findings are supported by mechanistic investigations that have identified multiple pathways through which environmental toxicants can induce DNA fragmentation in spermatozoa, including oxidative stress, mitochondrial dysfunction, and direct genotoxic effects (67)