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As noted previously, enlargement means that the size of the heart has gotten bigger over time

doi: 10.1093/aje/kwu283 70

As a negative regulator of Nrf2, GSK-3 sees a reduction in protein activity upon phosphorylation, with protein activity decreasing proportionally to the degree of phosphorylation

Whenever the number of samples was smaller than 30, and the data did not distribute normally ( P 1 or 50% of the reads were mapped to different tRFs (each color represents a single tRF