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3 In one study, healthy smokers were randomized to switch to e-cigarettes with varying nicotine levels or to not switch to e-cigarettes

As smoking is also common among alcohol drinkers, and smokers and drinkers frequently share similar behavioural and lifestyle patterns, it is currently unclear whether it is the combined or independent effects of smoking and alcohol that greatly raises cardiovascular risk

In bivariate and adjusted models predicting always crushing the flavour capsule for the USA, women were more likely to always crush than men (AOR=4.17, 95% CI 1.53 to 11.36, p=0.005) and those who intended to quit were less likely to always crush (AOR=0.21, 95% CI 0.08 to 0.57, p=0.002)