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As an example, the enrichment of genes associated with emphysema severity among genes changing with TGF treatment in the dataset from Malizia et al .[23] is shown in Figure 4a,b

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[10] Gastrointestinal disturbances-including nausea, loose stools, and a transient fishy body-odor attributable to trimethylamine production from excessive carnitine and choline metabolism-occur in a minority of recipients and are usually self-limiting within 24 to 48 hours after injection

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