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Statins Statins are lipid-lowering drugs that prevent cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase, commonly used in treating hypercholesterolemia and cardiovascular-related diseases [151]

In particular, it remains unknown whether ferroptosis inducers can simultaneously induce ferroptosis of cancer cells and immune cells to comprise the bodys immune function, and how ferroptosis inducers can modulate different immune cells to enhance or weaken the bodys immune response

demonstrated that the depletion or inhibition of arginine did not influence M

Proc Natl Acad Sci U S A (1995) 92(19):87059.10.1073/pnas.92.19.8705 38 BrunnGJFallsELNilsonAEAbrahamRT