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The central regulatory role of CHOP in these death pathways establishes its function as a molecular switch that determines cell survival or death under stress conditions

Furthermore, we focus on the role of protein glutathionylation recently found in fused-in-sarcoma (FUS)-associated ALS and discuss whether this glutathionylation has a pathological role in the development and progression of ALS by modulating LLPS of RBPs, particularly FUS

Conclusion: In large artery atherosclerotic stroke, bridging IVT before thrombectomy for LVO was associated with accelerated recanalisation, whereas cardioembolic stroke appeared to delay recanalisation when distal thrombus migration was observed

ZUMA-2: A phase 2 multicenter study evaluating the efficacy of KTE-C19 (anti-CD19 CAR T cells) in subjects with relapsed/refractory mantle cell lymphoma (r/r MCL)