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requires discipline to inject at the same time nightly Carpal tunnel risk Extended nighttime GH elevation can occasionally cause mild carpal tunnel symptoms (rare, usually resolves with dosage adjustment) Injection discomfort Some patients find evening injection timing causes next-day soreness, especially if theyre not accustomed to evening needles Less acute energy boost You wont feel the daytime energy spike that morning injection provides Best For: Patients prioritizing body composition changes, those with flexible daytime schedules, and people willing to maintain strict evening routines