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To determine whether HDAC9 is necessary for synaptic plasticity in the hippocampus, extracellular recordings of field excitatory postsynaptic potentials (fEPSPs) were conducted in the CA1 area of hippocampal slices from HDAC9 / mice and their WT littermate controls, specifically targeting synapses in the stratum radiatum, where Schaffer collateral inputs from CA3 neurons terminate on the apical dendrites of CA1 pyramidal neurons (Fig

This has made the peptide relevant to studies of energy balance, nutrient response, and metabolic adaptation

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