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doi: 10.1080/21655979.2022.2049471 366 ZhangYZhouXLiangGCuiMQiuZXuJet al

The accumulation of lipid droplets, rich in polyunsaturated fatty acids (PUFAs), also creates vulnerability to ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation [18, 19]