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Another potential site at which SOD mimics emulate the catalytic activities is the mitochondrial matrix

Seikagaku 2008 Apr;80(4):277-86

Am J Dermatopathol 27(2):96101 Ogbechie-Godec OA, Elbuluk N (2017) Melasma: an up-to-date comprehensive review

Melanotan-1's molecular weight (1646 Da) places it below the glomerular filtration threshold, allowing direct excretion through kidneys without requiring hepatic metabolism