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Zhao 2011

have demonstrated that homozygous carriers of SLC47A1 rs2289669 A-allele show a larger reduction in HbA1c to metformin therapy compared to the prevalent G-allele ( Pharmacogenomics studies have identified additional genetic variations associated with changes in metformin response in diverse populations

Indeed, cetuximab which is an epidermal growth factor receptor (EGFR) monoclonal antibody, has been approved by FDA as a radiation-sensitizer, alone or in combination with chemotherapy for patients with recurrent or metastatic diseases