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Toxicological Relevance of the Multidrug Resistance Protein 1, MRP1 (ABCC1) and Related Transporters

The Commission chief also said the bloc was bringing forward an order for delivery of 50 million doses of the vaccine to the second quarter of this year, after makers of the Johnson & Johnson vaccine suspended their deliveries

doi: 10.1126/science.2237407 16 FikrigE

25 Similarly, bilirubin also targets mitochondrial membranes, leading to disruption of the electron transport chain and membrane-bound proteins, which in turn results in mitochondrial swelling, membrane permeability, depolarization, cytochrome c release and cell death by apoptosis and necrosis