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[1] [2] However, the situation becomes more complex when fatty liver disease progresses to non-alcoholic steatohepatitis (NASH) , characterised by inflammation and liver cell damage, or advances to fibrosis or cirrhosis

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The assembly intermediate structure shows that the FrdA subunit is crosslinked with its assembly factor SdhE, potentially forming a channel to the active site

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PMID: 201 JacksonMRAshtonMKoessingerALDickCVerheijMChalmersAJ

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