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Melanocytic activation is an increase in the production and deposition of melanin into the nail cells (onychocytes), without an increase in the number of melanocytes

Si des symptmes persistent ou s'aggravent, ou si vous remarquez d'autres symptmes, veuillez contacter votre mdecin

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Not great for an entire PO regimen.) The IV protocol is a 20 hour treatment: Loading Dose: 150 mg/kg (max: 15 g) infused over 1 hour Second Dose: 50 mg/kg (max: 5 g) infused over 4 hours Third Dose: 100 mg/kg (max: 10 g) infused over 16 hours The PO protocol is a 72 hour treatment (rotten eggs for 72 hours!!): Loading Dose: 140 mg/kg Maintenance Dose: 70 mg/kg every 4 hours for a total of 18 doses NAC is typically the first-line option for the treatment of acetaminophen toxicity