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Agents such as sorafenib, sulfasalazine, and artesunate have shown efficacy in promoting ferroptotic death in tumor models, particularly in those resistant to apoptosis-based treatments ( Emerging evidence also suggests that ferroptosis is tightly coupled to lipid metabolism, membrane repair systems, and oxidative signaling

HC) from those appearing under repeated stress (e.g., HH vs

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Further, we highlight the therapeutic potential of ferroptosis inducers and inhibitors, including small molecular agents and natural active ingredients, for delaying the progression of liver diseases in preclinical models