Short-term, high level exposure to benzene through inhalation or ingestion can cause damage to the central nervous system leading to paralysis
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Though it was a commoditie that is nowe vendible in every Taverne, Inne, and Ale-house, as well as by apothecaries and grocers, Rich remarked, there was a Cathalogue taken of all those newly erected houses that have set uppe that Trade of selling Tobacco, in London & neare about London.Footnote 103 Since sellers are (almost) never without company, that from morning till night are still taking of Tobacco, these spaces evolved into open shoppes, that have no other trade to live by, but by the selling of tobacco.Footnote 104 Tobacco shops, wrote the satirist John Earle, were the Randevous of spitting where communication is smoke, a place, scandalously, where Spain is commended and preferd before England it selfe.Footnote 105 The reference to Spain may have alluded to Spanish-imported tobacco in England which, as another author noted, cannot but greatly prejudice the Common-weale but also to topics of political discourse, including travel news.Footnote 106 Published shortly after Richs description of Londons flourishing tobacco shops, a broadside promoting good table manners conveyed authorities attempts to regulate subjects manners while also disclosing the particular topics of discourse that tobacco seemed to encourage (Figure 5)
