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While its primary FDA approvals cover major depressive disorder, OCD, panic disorder, and bulimia nervosa, it is widely prescribed off-label for generalized anxiety disorder and social anxiety disorder

Further evidence suggests, but does not conclude, that smoking cessation was beneficial in reducing the risk of atrial fibrillation, sudden cardiac death without coronary artery disease, heart failure among former smokers, hospitalizations, peripheral arterial disease, and abdominal aortic aneurysm

Nicotine changes how the brain responds to stress and reward, which is why support often needs to go beyond just trying to stop

In 2021, the company was found liable for civil conspiracy and Greene was awarded the initial multi-million dollar judgment