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(2) Downstream protection with cartilage-building substrates (e.g., collagen peptides, vitamin D) to enhance matrix integrity (11, 12)

Capelli I, Cianciolo G, Gasperoni L, Zappulo F, Tondolo F, Cappuccilli M et al

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Additionally, increased levels of the hypoxia-induced transcription factor HIF-1 across retinal neurons and glia support the idea that RGCs undergo metabolic stress before overt glaucomatous progression (Williams et al., 2017)