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This can cause fatigue, pale skin, and shortness of breath, as the body struggles to transport oxygen efficiently

The hyper activation of HPA axis stimulate overproduction of cortisol, while down regulation of HPG axis results in the production of subnormal levels of gonadotropic hormones

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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Chen B., Dowlatshahi D., MacQueen G.M., Wang J.F., Young L.T