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For a comprehensive overview, see Scientific research on intravenous micronutrients

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2025 Oct 29;243(Pt 1):117481

Several trials and updated analyses indicate improvements in fasting insulin, HOMA-IR, BMI/waist indices, and lipid parameters, particularly among women with obesity or IR and low baseline 25(OH)D, whereas pooled estimates from other RCTs fail to show consistent effects on fasting glucose or HOMA-IR, likely reflecting underpowered studies and short follow-up (118)